Arran Schlosberg

MBBS, BCom (Actuarial Studies), CHIA
Clinical Associate Lecturer, Sydney Medical School

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Hello

I am a medical Doctor in Sydney, Australia with commercial and research backgrounds in data analysis, IT administration, software development, and client-centric business administration. Amongst other things my experience includes university teaching, and organisational strategy and leadership. In early 2014 I qualified as the inaugural Certified Health Informatician Australasia (CHIA).

I intend for this website to serve as a hybrid between an informal résumé and a place to showcase my creations—thus, please excuse the hubris.

Core Competencies

Highlights

Research & Development

  • Schlosberg A, Lam BYH, Yeo GSH, Clifton-Bligh RJ. DEFLATE Compression Algorithm Corrects for Overestimation of Phylogenetic Diversity by Grantham Approach to Single-Nucleotide Polymorphism Classification. International Journal of Molecular Sciences. 2014; 15(5):8491-8508.

    Non-synonymous single-nucleotide polymorphisms (nsSNPs) involve the substitution of a single DNA base-pair with a consequent change in protein function, often within a gene already known to be associated with disease. Novel nsSNPs in such genes require classification as disease-causing or neutral, a task partly achieved through statistical analyses.

    We demonstrated that data compression algorithms can be utilised to quantify genetic diversity amongst species and utilised these values to model known nsSNPs and appropriately classify novel ones with Bayesian updating of probabilities of disease-causation.

    An online tool is available for SNP classification.

  • Development of BarraCUDA

    NextGen sequencing data outputs snippets (known as reads) of genetic material. Measured in tens to hundreds of base-pairs as against the 3 billion or so in a full human genome, reads require alignment to a reference sequence, allowing for variation between the individual in question and the reference.

    BarraCUDA utilises the parallel processing of GPUs to increase the speed of the alignment process. My contribution, post original publication, was to generalise the breadth-vs-depth-first search approaches to allow for hybrid searching as well as streamlining memory transfers between CPU and GPU; this resulted in a 40% throughput increase without a reduction in accuracy.

Experience

  • Junior Medical Officer

    ; Hornsby Ku-ring-gai, Mona Vale, Manly, and Sydney Adventist Hospitals
    January 2014 - present
  • Founder, Director

    ; Oonix Pty Ltd
    February 2010 - present
    • Web-hosting and software-development company with technical functionality driven by automation of client tasks.
    • Automated business processes for industries including commercial property management, and retail.
    • Administration of Linux server infrastructure for web hosting:
      • Development of a custom server module allowing for decreased hardware requirements.
      • Automated diagnostic scripts for server monitoring and error correcting.
  • Information Technology Officer, Executive

    ; Australian Medical Students' Association
    January 2013 - December 2013
    • Member of team "tasked with day-to-day operations, leadership, strategic direction, and student representation".
    • Managed complex registration for National Convention using Amazon cloud-computing infrastructure; handled >$20,000/sec at peak and reduced costs by >95%.
    • Held talks with members of parliament regarding job shortages.
  • Lead Developer

    ; Click Ventures
    January 2009 - December 2009
    • Complete redevelopment and implementation of nightclub oriented social network with a user base of >120,000 members.
  • Technical Director

    ; Wispa Group Pty Ltd
    January 2008 - December 2008
    • Development of technical solutions for digital marketing agency; predominantly database driven web applications.
  • Casual Academic Staff

    ; Macquarie University
    January 2007 - July 2008

Education & Certification

Photography

A small selection of my favourites; taken in Sydney, New York, and Israel.

© 2014 Arran Schlosberg
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